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diffdock

This skill wraps the DiffDock tool for predicting 3D binding poses of small molecules to proteins using diffusion models. It handles PDB files or protein sequences and SMILES strings or ligand files, outputs multiple ranked poses with confidence scores, and supports batch processing for virtual screening. It clearly states it predicts poses, not binding affinity.

Packaged view

This page reorganizes the original catalog entry around fit, installability, and workflow context first. The original raw source lives below.

Stars
15,475
Hot score
99
Updated
March 20, 2026
Overall rating
A8.3
Composite score
6.8
Best-practice grade
N/A

Install command

npx @skill-hub/cli install k-dense-ai-claude-scientific-skills-diffdock
molecular-dockingdrug-discoveryprotein-ligandcomputational-chemistrydiffusion-models

Repository

K-Dense-AI/claude-scientific-skills

Skill path: scientific-skills/diffdock

This skill wraps the DiffDock tool for predicting 3D binding poses of small molecules to proteins using diffusion models. It handles PDB files or protein sequences and SMILES strings or ligand files, outputs multiple ranked poses with confidence scores, and supports batch processing for virtual screening. It clearly states it predicts poses, not binding affinity.

Open repository

Best for

Primary workflow: Research & Ops.

Technical facets: Data / AI.

Target audience: AI/ML teams looking for install-ready agent workflows..

License: Unknown.

Original source

Catalog source: SkillHub Club.

Repository owner: K-Dense-AI.

This is still a mirrored public skill entry. Review the repository before installing into production workflows.

What it helps with

  • Install diffdock into Claude Code, Codex CLI, Gemini CLI, or OpenCode workflows
  • Review https://github.com/K-Dense-AI/claude-scientific-skills before adding diffdock to shared team environments
  • Use diffdock for ai/ml workflows

Works across

Claude CodeCodex CLIGemini CLIOpenCode

Favorites: 0.

Sub-skills: 0.

Aggregator: No.

diffdock | SkillHub